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Jian Wang Selected Research

Monocrotaline

1/2022Gut Microbial Metabolite Trimethylamine N-Oxide Aggravates Pulmonary Hypertension.
1/2021Combination Therapy With Rapamycin and Low Dose Imatinib in Pulmonary Hypertension.
1/2021PDGF/MEK/ERK axis represses Ca2+ clearance via decreasing the abundance of plasma membrane Ca2+ pump PMCA4 in pulmonary arterial smooth muscle cells.
1/2021Upregulation of Calcium Homeostasis Modulators in Contractile-To-Proliferative Phenotypical Transition of Pulmonary Arterial Smooth Muscle Cells.
2/2020Inhibition of Siah2 ubiquitin ligase ameliorates monocrotaline-induced pulmonary arterial remodeling through inactivation of YAP.
1/2020Direct Extracellular NAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling. Transcriptional Regulation by SOX and HIF-2α.
1/2020Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension.
1/2019Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension.
1/2019Paclitaxel alleviates monocrotaline-induced pulmonary arterial hypertension via inhibition of FoxO1-mediated autophagy.
10/2018Resveratrol inhibits monocrotaline-induced pulmonary arterial remodeling by suppression of SphK1-mediated NF-κB activation.
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Jian Wang Research Topics

Disease

858Neoplasms (Cancer)
12/2022 - 01/2002
162Inflammation (Inflammations)
09/2022 - 06/2005
129Neoplasm Metastasis (Metastasis)
10/2022 - 01/2002
119Infections
07/2022 - 01/2003
99Hypoxia (Hypoxemia)
07/2022 - 02/2005
97Hepatocellular Carcinoma (Hepatoma)
12/2022 - 06/2003
76Breast Neoplasms (Breast Cancer)
05/2022 - 12/2002
74Fibrosis (Cirrhosis)
07/2022 - 06/2002
73Pain (Aches)
12/2022 - 05/2005
73Parkinson Disease (Parkinson's Disease)
05/2022 - 07/2002
72Carcinogenesis
08/2022 - 04/2003
69Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2022 - 10/2008
64Glioma (Gliomas)
10/2022 - 10/2006
59Lung Neoplasms (Lung Cancer)
07/2022 - 03/2003
57Stroke (Strokes)
12/2022 - 11/2003
56Prostatic Neoplasms (Prostate Cancer)
01/2022 - 11/2002
55Stomach Neoplasms (Stomach Cancer)
04/2022 - 01/2008
54Pulmonary Hypertension
01/2022 - 06/2006
52Glioblastoma (Glioblastoma Multiforme)
03/2022 - 04/2006
49Carcinoma (Carcinomatosis)
01/2022 - 01/2003
48Hemorrhage
06/2022 - 03/2005
48Wounds and Injuries (Trauma)
05/2022 - 11/2006
43Ischemic Stroke
06/2022 - 01/2005
40Cerebral Hemorrhage
01/2022 - 11/2003
39Chronic Obstructive Pulmonary Disease (COPD)
08/2022 - 12/2010
38Type 2 Diabetes Mellitus (MODY)
01/2022 - 06/2002
36COVID-19
10/2022 - 01/2020
35Brain Ischemia (Cerebral Ischemia)
01/2022 - 07/2004
34Body Weight (Weight, Body)
06/2022 - 04/2002
34Colorectal Neoplasms (Colorectal Cancer)
05/2022 - 05/2003
34Pulmonary Arterial Hypertension
02/2022 - 09/2007
34Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 05/2003
34Leukemia
11/2021 - 08/2005
33Alzheimer Disease (Alzheimer's Disease)
01/2022 - 07/2007
32Chronic Hepatitis B
04/2022 - 11/2006
32Vascular Remodeling
01/2022 - 09/2007
31Liver Cirrhosis (Hepatic Cirrhosis)
01/2022 - 04/2005
30Hypertension (High Blood Pressure)
12/2022 - 06/2002
30Thrombosis (Thrombus)
10/2022 - 04/2002
30Brain Injuries (Brain Injury)
01/2022 - 07/2005
29Sepsis (Septicemia)
10/2022 - 09/2010
29Ischemia
01/2022 - 01/2003
28Lymphatic Metastasis
01/2021 - 01/2005
27Obesity
12/2022 - 01/2007
27Insulin Resistance
12/2021 - 01/2002
26Necrosis
01/2022 - 02/2002
26Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022 - 02/2005
26Pancreatic Neoplasms (Pancreatic Cancer)
10/2021 - 03/2005
25Infarction (Infarctions)
04/2022 - 04/2006
25Neuroinflammatory Diseases
04/2022 - 09/2012
25Cognitive Dysfunction
01/2022 - 03/2010
24Heart Failure
03/2022 - 01/2003
24Autoimmune Diseases (Autoimmune Disease)
01/2022 - 08/2005
24Spinal Cord Injuries (Spinal Cord Injury)
01/2022 - 03/2006
24Asthma (Bronchial Asthma)
01/2022 - 06/2005
23Liver Diseases (Liver Disease)
05/2022 - 04/2005

Drug/Important Bio-Agent (IBA)

312Proteins (Proteins, Gene)FDA Link
08/2022 - 02/2002
173Biomarkers (Surrogate Marker)IBA
05/2022 - 06/2004
130Pharmaceutical PreparationsIBA
12/2022 - 01/2003
121Messenger RNA (mRNA)IBA
05/2022 - 07/2002
109Biological ProductsIBA
12/2022 - 02/2002
105CytokinesIBA
07/2022 - 05/2002
102MicroRNAs (MicroRNA)IBA
06/2022 - 02/2009
66DNA (Deoxyribonucleic Acid)IBA
04/2022 - 10/2002
62Therapeutic UsesIBA
08/2022 - 06/2002
60RNA (Ribonucleic Acid)IBA
10/2022 - 01/2002
55Long Noncoding RNAIBA
09/2022 - 05/2012
54Glucose (Dextrose)FDA LinkGeneric
06/2022 - 07/2004
46Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2021 - 01/2002
45EnzymesIBA
10/2022 - 06/2002
43AntigensIBA
10/2022 - 01/2005
38Interleukin-6 (Interleukin 6)IBA
09/2022 - 11/2006
38IronIBA
01/2022 - 10/2002
38LipidsIBA
01/2022 - 07/2007
37Phosphotransferases (Kinase)IBA
10/2022 - 09/2004
37LigandsIBA
10/2022 - 01/2002
37Transcription Factors (Transcription Factor)IBA
10/2022 - 08/2005
37Small Interfering RNA (siRNA)IBA
01/2022 - 11/2008
35Reactive Oxygen Species (Oxygen Radicals)IBA
04/2022 - 06/2006
33CollagenIBA
12/2022 - 10/2004
33VaccinesIBA
10/2022 - 08/2003
32Indicators and Reagents (Reagents)IBA
07/2022 - 04/2003
31Cisplatin (Platino)FDA LinkGeneric
02/2022 - 09/2007
29Anti-Bacterial Agents (Antibiotics)IBA
10/2022 - 10/2013
28LipopolysaccharidesIBA
07/2022 - 03/2010
27AntibodiesIBA
01/2022 - 02/2002
26AntioxidantsIBA
06/2022 - 05/2003
24Peptides (Polypeptides)IBA
06/2022 - 03/2006
24Neuroprotective AgentsIBA
12/2021 - 11/2003
23CateninsIBA
06/2022 - 11/2010
23Antiviral Agents (Antivirals)IBA
05/2022 - 12/2003
23SmokeIBA
01/2022 - 03/2003

Therapy/Procedure

355Therapeutics
12/2022 - 01/2002
108Drug Therapy (Chemotherapy)
12/2022 - 12/2004
62Radiotherapy
01/2022 - 03/2003
50Immunotherapy
08/2022 - 02/2004
42Transplantation
02/2022 - 03/2006
41Chinese Traditional Medicine (Traditional Chinese Medicine)
02/2022 - 08/2010
24Aftercare (After-Treatment)
01/2022 - 06/2002
23Ligation
12/2021 - 02/2005